Oh, I'm sure some kind of modification to the aetherflux reservoir combo. It's much better than reservoir: don't need to target opponent, costs less and you only need to dump things in the GY
It does need to target an opponent though. It says target opponent loses the game, not that you win the game.
Not sure how well this plays with infect, since the wurm doesn't have trample, and would appear to overwrite any keywords the target creature already had.
It does need to target an opponent though. It says target opponent loses the game, not that you win the game.