Leyline of Sanctity is much tougher to deal with, but if you play Empty the Warrens (which you almost definitely should in at least sideboard, I personally have one copy mainboard) you can overwhelm with goblins, which bypass Leyline.
If for some reason you don't have Empty or don't draw it, any bounce spell will do the job too, Echoing Truth being probably the most effective as it can bounce multiple Leylines (if that comes up).
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