Is your Madness experiment still going, and have you incorporated Terminal Agony? Seems like an auto-include, but I didn't see it in your initial list of cards despite other MH2 stuff being listed.
Additionally, I'm sure certain mechanics "play nice" with the Madness archetype as well - providing pseudo-support, if you will. Stuff like Retrace, Flashback, Jumpstart, Cycling, etc... can either provide stuff you wouldn't feel horrible about discarding or stuff that provides easy discard outlets on the side.
Also, what about stuff like Careful Study, Cathartic Reunion, Desperate Ravings, Tormenting Voice, etc... as enablers? oh... Fissure Wizard too.
Additionally, I'm sure certain mechanics "play nice" with the Madness archetype as well - providing pseudo-support, if you will. Stuff like Retrace, Flashback, Jumpstart, Cycling, etc... can either provide stuff you wouldn't feel horrible about discarding or stuff that provides easy discard outlets on the side.