Huge fan of Go for the Throat as Path #5, Spellskite can't redirect it, and Affinity is a good match anyway. I would not run Doom Blade with Tasigur, Kalitas, Bob, Siege Rhino, and Angler all significant in the larger meta. Definitely agree that Wastes in the main is worth a look.
Dismember kills all of those mentioned cards as well, and can be cast off of an eldrazi scion or an eldrazi temple.
Sure Spellskite can redirect it but since when does this deck have a problem with spellskite?
I think with some of the new cards spoiled, mono-black eldrazi processors can be a thing.
We would lose Lingering Souls, Path, Sorin but gain the new 3 drop, distended mindbender, and we can replace path with any number of black removal spells. I will certainly consider this once I start playtesting with the new stuff.