If someone activates pernicious deed since its a sacrifice in the cost does it go on the stack or instantly sac. I know in the reverse like sacrifice in response to a bolt just wastes a lightning bolt essentially. But if pernicious deed is activated could I respond with and instant with destroy target permanent or enchantment or will deed still resolve and id be wasting a removal.
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-MadMage
Sacrificing Pernicious Deed is a cost, and you can't respond to costs. You can only respond to an activated ability once it's fully activated and paid for. What goes on the stack is only what's after the colon, "destroy each...". What's before the colon is the cost. When you get priority (the right to cast spells or activate abilities), Pernicious Deed is already gone. You can't even try and waste your removal spell (let's say it's Disenchant), since you can't cast it on a nonexistent target.
Also note that even if the Deed's ability didn't require sacrificing it, and you could destroy it in response to the ability, that still wouldn't stop the ability. Once activated, an ability is independent from its source.
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-MadMage
Also note that even if the Deed's ability didn't require sacrificing it, and you could destroy it in response to the ability, that still wouldn't stop the ability. Once activated, an ability is independent from its source.