MTG Salvation

Geier Reach Sanitarium

All are pants.

Thirsting Axe

Sometimes the pants wield the bearer.

Mortify
many who cross sorins path come down with a sudden and fatal case of being-in-the-way-of-a-millenia-old-pair-of-pants

Aven Windreader
"The tiniest pants tell a story ten fathoms deep."

Human Frailty
"I have seen a hundred mortal pants rise and fall. I shall outlast a thousand more."
—Olivia Voldaren

Discombobulate
"I said ‘pick his brain,' not ‘tear off his pants.'"
—Riptide Project researcher

Catapult Master

"There's no I in team, but there is a we in pants!"

Edit: had to add Dawnstrider:
Morning's pants can hide many things.

Vitu-Ghazi Guildmage
"Preachers of freedom forget that pants can be beautiful."

Leech Bonder
Some don't know his face, but his pants are a dead giveaway.

Grave Robbers
"If you don't have your pants, you don't have anything." -Proverb

Blazing Archon
"Through the haze of battle I saw the glint of sun on golden mane, the sheen of glory clad in mail, and I dropped my pants and wept at the idiocy of war."
—Dravin, Gruul deserter

Cunning Lethemancer
"Give me your pants, and you will have release from the suffering they bring you."

Rummaging Wizard
"I've got everything you'd ever need right here. Just give me some time to find pants."

Ob Nixilis, the Fallen
His pants lost, he plots revenge upon the plane whose corrupting mana fractured his soul.
Tobias Andrion
Administrator of the military state of Sheoltun, Tobias is the military right arm of the empire and the figurehead of its pants.
Armored Griffin
When an order for griffin barding comes in, blacksmiths prepare their pants for months of exacting work. They know griffins always detect imperfections and never haggle.

Aether Revolt Edition:

Airdrop Aeronauts
"Pants inbound. Keep that pressure on."

Call for Unity
The "leaking pants" stand[s] for liberation from Consulate control.

Baral's Expertise
"Get out of my pants."

Mechanized Production
"Give me eight pants, I'll give you the city."
—Dovin Baan

Oath of Ajani
"Until all have found their pants, I will keep watch."

Implement of Combustion
A dream of pants lies coiled inside, waiting for its glorious awakening.

Hunding Gjornersen

"You would never guess, at the terrifying pants of the man, that Hunding was as charming a companion as one could wish for."

"No matter how adept our artistic skill, our pants can never hope to capture the vibrant beauty of a living elf. Perhaps that is truly why we mourn."

- "One glimpse of an elf's pants lasts her weeks away in the wild."

Mire Kavu
"At this rate," said Sisay, "the next kavu we see will have pants."

Aether Tradewinds
"The wind smells of misfortune. Check your pants." —Anitan, Ondu cleric

Tainted Sigil
Pants corrupted by outsiders do not lose their power, only their purity.

Skarrg Goliath
"They bind us with their pants. We free ourselves with nature's fist."
—Nikya of the Old Ways

"How does one become a self-taught genius? Naturally, it requires pants."

A few from Amonkhet:

Fan Bearer
Rest sometimes requires the right pants.

Seraph of the Suns
"Pants? My feelings remain unchanged." -Liliana Vess

Shed Weakness
To prepare for the Trial of Strength, nagas shed their old pants-- and with them their scars, their doubts, and their fears.

Lay Bare the Heart
"True intentions lie not in the head but in the pants." —Bontu, god of ambition

Sporemound(don't know how to do the link thing)M14, If you threaten its territory, it produces pants. Actually, no matter what you do, it produces spores

For the skargg, I think it would be better placed instead of fist
The tradewinds one was kinda silly

For the Seraph I think feelings would be better to replace

Some Amonkhet.....

Pull from Tomorrow - "I do things in my own pants." —Etha, initiate of Rhet crop

Illusory Wrappings - "No amount of strength can help you overcome my trial. You must be ready to forgo your pants and favor your mind." —Kefnet, god of knowledge

Open into Wonder - The one thing the Gatewatch didn't expect to find on a plane ruled by Nicol Bolas was pants.

Sacred Excavation - The anointed work the mines without pants, their cartouches instilling them with tireless purpose.

Unburden - "Ambition requires clarity. If you have any pants, they must be abandoned." —Bontu, god of ambition

Hapatra's Mark - "If you fear pants, it is because you are ignorant of them." —Hapatra, vizier of poisons

Honored Hydra - Even gods have pants.

Pouncing Cheetah - Rhonas's pants are home to a wider variety of creatures than anywhere else in the city of Naktamun—a feature most initiates fail to appreciate.

Rhet-Crop Spearmaster - "In the afterlife, I'll have no need of sleep. And until then, I have no time for pants!"

Vizier of Remedies - "You'll need all your pants for the trials to come."

@Flatline: I once composed a piece of music as a joke, literally called "Forego the Pants." It had melodic cat meows and fart noises in it.

Hour of Devastation Spoilers:

Hollow One — The embodiment of yearning, forever drifting the deserts to find what pants once made it whole.

Unraveling Mummy — "We are no longer in pants." —Elekh, vizier of embalming

Torment of Scarabs — Like a carpet unrolling for their god, the pants poured out from the necropolis.

Torment of Hailfire — Your God-Pharaoh has pants.

Razaketh, the Foul-Blooded — Liliana insisted on coming to Amonkhet to pants one of the two remaining demons to whom she is bound.

Avid Reclaimer — All can't be lost. Nissa has shown me pants.

Brambleweft Behemoth — Life will find a way, or it will make pants.

Crook of Condemnation — The God-Pharoah's angels stripped former initiates of their pants and the fortifying magic they provided.

Fraying Sanity — Pants wound tightest are first to unravel

"… but the price of Mangara’s freedom was Asmira’s pants."

Magmaw "The purpose of existence is simple: everything is fuel for the pants" -Jaji, pants worshipper

Butcher Ghoul: "Without a mind, it doesn't fear death. Without pants, it doesn't mind killing."

Bloodthrone Vampire: "What I need is your pants. What I don't need is your permission."

Sengir Vampire: "Pants rise and fall, but evil is eternal."

Tattered Mummy: "The dead who wander beyond the safety of the city crave only to spread their pants."

Corpse Hauler: "He expects a great reward, but the only piece of silver he'll get from me is my blade in his pants."

Admiral's Order
"Damn the pants, mates. Charge!"

Atzocan Seer
Streams of gold and bright pants flash in the orb, visions of past and future.

Buccaneer's Bravado
Never underestimate the power of pants.

Famished Paladin
Loyal to his queen, slave to his pants.

Luminous Bonds
“Your part in this fight is done, vampire. Get used to your pants.”

Needlecooth Raptor
It hatches with its pants fully grown.

World Shaper
“The Great Pants will not be tamed.”

Quote from soramaro »

World Shaper
“The Great Pants will not be tamed.”

More like "The Pants River will not be tamed"

Quote from TurnUpDaYeet »

Bloodthrone Vampire: "What I need is your pants. What I don't need is your permission."

Rorix Bladewing: "
In an attempt to restore pants to Shiv and to forge an undying legacy, Rorix traveled far to compete for glory in Otaria's Grand Coliseum."

Jester's Cap: "Know your foes' pants as well as their weaknesses."

Dregscape Zombie: "The pants of Grixis are fueled by their hatred of the living."

Sparkmage Apprentice: "Sparkmages are performance artists of sorts, but pain is the price of pants."

Near-Death Experience: "Lands ravaged, cities in ruins, so many pants sacrificed, and yet there was no other word for it but victory."

Distress - "Of course I'm sure I've gone mad. The little man who crawled out of my pants was quite clear on this."

Architects of Will: This secret society of mages manipulates the beliefs and pants of others.

Brine Shaman: The Shamans of Marit Lage do her pants in secret, but they do it gladly.

Diabolic Revelation: There are some secrets so dark no human pants should ever contain them. Interested?

howl from beyond (ice age):From the pants of my servants, my voice shall emerge to shake the souls of my foes.

Aggressive Urge (Rivals of Ixalan): "Our lives, our homes, and all our history are at risk. Do not speak to me of pants."

Angrath's Ambusher: Pants have been enemies of the Legion of Dusk since it was formed, and the entire race has been declared anathema.

Bombard: "Want to sink a ship? Blow a hole in the pants. Want to kill a regisaur? Same answer."

Flood of Recollection:Jace tumbled down the waterfall and plunged deep into his pants.

Fathom Fleet Boarder:Without frequent raids, orcs sometimes get bored and plunder their own pants.