Once Sanctum goes it would probably go back to a Brain in the Jar list and while some builds use Day's Undoing, it's not the end of the world if it goes as you can opt to just run more Rise from the Tides instead. Hydrolash would probably have the biggest impact when it goes, but even that can be mitigated by Thing in the Ice. And this isn't even considering what cards might be released with Kaladesh.
I agree, Jace's Sanctum becomes Brain in a Jar. Hydrolash could be Chilling Grasp. I used that along side Hydrolash last FNM and it performed much better than expected. We lose the hitting every creature effect and the cantrip but unless something better comes out in Kaldesh then that's where I think we are going. The card I'm most concerned with losing is Prism Ring. It's such an amazing card in this deck and there really isn't anything that I can think of that would help fill its role. Hoping on Kaladesh for that one.
how do we handle big creature decks, specifically eldrazi. i went 3-1 tonight at fnm losing only to a weird totally colorless eldrazi list. the smaller ones like matter reshaper or even oblivion sower were fine enough, but once they got enough for ulamog/kozilek i kinda just fell apart.
We lose