No. The first thing that happens is Guide triggers and its trigger tries to go onto the stack. During this time, you declare a target for the trigger, Once that is done, you get priority but you have already chosen a target for the trigger so sacrificing Guide will not allow you to change the target.
No, because you have to choose the target for the Guide's ability as you put it on the stack, which is before you get priority to activate the Altar.
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I'm a former judge (lapsed), who keeps up to date on rules and policy. Keep in mind that judges' answers aren't necessarily more valid than those of people who aren't judges; what matters is we can quote the rules to back up our answers. When in doubt, ask for such quotes.
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Karmic Guide and Ashnod's Altar